| Set It Off | 7 | 1 |
| Seu Jorge | 1 | 1 |
| Seun Kuti | 1 | 1 |
| Sevara Nazarkhan | 1 | 1 |
| Seven Lions | 7 | 1 |
| Shaboozey | 4 | 1 |
| Shafiq Husayn | 2 | 1 |
| Shakatak | 0 | 1 |
| Shaking Hand | 1 | 1 |
| Shakin’ Street | 1 | 1 |
| Shane MacGowan and the Popes | 1 | 1 |
| Shape of Despair | 1 | 1 |
| Sharon Jones and the Dap‐Kings | 1 | 1 |
| Sharp Pins | 5 | 1 |
| Shawn Colvin | 13 | 1 |
| Shawn Desman | 1 | 1 |
| Shearling | 1 | 1 |
| Shearwater | 2 | 1 |
| Sheep, Dog & Wolf | 1 | 1 |
| Sheer Mag | 1 | 1 |
| Sheikh Ahmad Barrayn | 1 | 1 |
| Sheila Jordan | 7 | 1 |
| Shelley Fabares | 1 | 1 |
| Shelleyan Orphan | 1 | 1 |
| Shining | 8 | 1 |
| Shinobu | 1 | 1 |
| Shirley Bassey | 35 | 1 |
| Shirley Scott | 9 | 1 |
| Shlohmo | 7 | 1 |
| Shontelle | 4 | 1 |
| Shout Out Louds | 6 | 1 |
| Shrimp Boat | 4 | 1 |
| Shye | 1 | 1 |
| Shye | 1 | 1 |
| Sibylla Rubens | 12 | 1 |
| Sic Alps | 4 | 1 |
| Sick Pleasure | 1 | 1 |
| Side by Side | 1 | 1 |
| Sidney Bechet | 21 | 1 |
| Sienna Spiro | 1 | 1 |
| Sienna_Sleep | 1 | 1 |
| Sierra Ferrell | 1 | 1 |
| Sigh | 1 | 1 |
| Sightseeing Crew | 1 | 1 |
| Signor Benedick the Moor | 1 | 1 |
| Sikter | 1 | 1 |
| Silbermond | 1 | 1 |
| Silk Road Ensemble | 10 | 1 |
| Silkworm | 11 | 1 |
| Silverfish | 2 | 1 |
| Simon Finn | 1 | 1 |
| Simon Preston | 65 | 1 |
| Sin Fang | 7 | 1 |
| Sinfonia of London | 30 | 1 |
| Sinfóníuhljómsveit Íslands | 58 | 1 |
| Singers of the Art of Living | 1 | 1 |
| Sinikka Langeland | 3 | 1 |
| Sinkane | 1 | 1 |
| Sinoia Caves | 0 | 1 |
| Sir Douglas Quintet | 1 | 1 |
| Sir Lord Von Raven | 2 | 1 |
| Sir Peter Maxwell Davies | 54 | 1 |
| Sirplus | 0 | 1 |
| Sisa | 15 | 1 |
| Sisso | 3 | 1 |
| Sister Rosetta Tharpe | 18 | 1 |
| Sitompul Sisters | 1 | 1 |
| Skaldowie | 1 | 1 |
| Skarazula | 1 | 1 |
| Skepticism | 1 | 1 |
| Skids | 8 | 1 |
| Skin Alley | 1 | 1 |
| Skip Bifferty | 1 | 1 |
| Skip James | 9 | 1 |
| Skream | 3 | 1 |
| Skullcrusher | 2 | 1 |
| Sky Rompiendo | 1 | 1 |
| SkyTwoHigh | 23 | 1 |
| Skálmöld | 6 | 1 |
| Skúli Sverrisson | 4 | 1 |
| Slaughter | 1 | 1 |
| Slava Ganelin | 0 | 1 |
| Sleeping at Last | 1 | 1 |
| Sleepy Sun | 5 | 1 |
| Slobberbone | 6 | 1 |
| Sloche | 2 | 1 |
| Sloppy Jane | 1 | 1 |
| Slow | 0 | 1 |
| Slum Village | 18 | 1 |
| Smak | 1 | 1 |
| Smash Mouth | 11 | 1 |
| Smerz | 3 | 1 |
| Smokie | 1 | 1 |
| Snake | 1 | 1 |
| Snapcase | 1 | 1 |
| Snatam Kaur | 1 | 1 |
| Sneaker Pimps | 1 | 1 |
| Snocaps | 1 | 1 |
| Snot | 1 | 1 |
| Snowing | 0 | 1 |